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uniQure Stock Price Target Raised on Blockbuster Opportunity

Asktraders News Team trader
Updated 2 Oct 2025

uniQure N.V. (NASDAQ: QURE) has seen its stock price target significantly increased by Wells Fargo, signaling strong confidence in the biotechnology company's gene therapy programs and potential for future growth. The upward revision reflects positive sentiment surrounding uniQure's lead candidate, AMT-130, and its potential to address a significant unmet medical need.

The stock closed at $54.99 yesterda, experiencing a 5.79% decrease from the previous day's trading, and has moved flat on today's session after testing $57. Despite this short-term dip, the broader market sentiment surrounding uniQure remains optimistic, fueled by analyst upgrades and promising clinical data. The current price reflects a degree of investor caution, but the potential upside remains substantial given the company's pipeline and recent positive assessments.

Wells Fargo increased its price target on uniQure to $80 from $65, reaffirming an Overweight rating on the shares. This decision was influenced by favorable key opinion leader perspectives on three-year data related to AMT-130. These experts voiced confidence in patients actively seeking AMT-130 treatment and in centers developing effective strategies to administer the product. Wells Fargo continues to view uniQure as holding blockbuster potential, driven by the compelling product profile of its gene therapy programs.

Prior to this, Wells Fargo had already adjusted its price target upwards from $30.00 to $65.00 on September 25, demonstrating a consistent bullish outlook. The consensus among 12 analysts currently places the average price target at $65.08, suggesting a potential upside of approximately 18.35% from the current trading price. Notably, the highest price target among analysts stands at $95.00, reflecting significant optimism regarding the company's long-term growth prospects. This wide range in price targets highlights the inherent uncertainty in valuing biotechnology companies, particularly those developing novel gene therapies.

uniQure, a biopharmaceutical company specializing in gene therapies, is focused on developing treatments for severe genetic diseases. The company's lead product candidate, AMT-130, is being investigated as a potential treatment for Huntington's disease, a devastating neurodegenerative disorder. Positive clinical data from ongoing trials of AMT-130 are crucial to maintaining the positive market sentiment and achieving the ambitious price targets set by analysts. The success of AMT-130 is seen as the key driver for future growth and market dominance in its therapeutic area.

The revised price targets and ongoing analyst coverage underscore a positive outlook for uniQure's stock, contingent on continued clinical success and market adoption of its gene therapy products. The current market valuation presents a potentially attractive entry point for investors who believe in the long-term potential of gene therapy and uniQure's ability to execute its clinical and commercial strategy.

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