Arrowhead Pharmaceuticals (NASDAQ: ARWR) stock has climbed over 45% higher after the company announced positive interim results from its Phase 2 study of ARO-AAT in treating a rare genetic liver disease.
Arrowhead said that the therapeutic, which is being used in the study to treat a rare genetic liver disease associated with alpha-1 antitrypsin deficiency (AATD), showed clear evidence of a meaningful effect leading to improvements in patients.
“The improvements in additional clinically meaningful biomarkers, including reductions in Z-AAT polymer, improvements in FibroScan values, and decreases in ALT and GGT, were more substantial than we expected,” said Javier San Martin, MD, chief medical officer at Arrowhead.
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Arrowhead shares…
The news resulted in a leap in Arrowhead’s share price. It closed Wednesday’s trading session at $33.80 and is currently trading at $49.22 per share, up over 45%.
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